“I solemnly swear that I am up to no good”

Nick Mahtani

Biomedical Engineer & Computational Biologist

Building at the intersection of organoid biology and computation.
EPFL graduate. Harvard research alumnus.

About

Nick Mahtani

I'm a biomedical engineer from EPFL with a deep passion for tissue engineering and organoid biology. My research journey has taken me from mechanical engineering at the American University of Sharjah to stem cell bioengineering at EPFL and biomaterials at Harvard's Mooney Lab.

Throughout my master's, I deliberately worked across multiple labs, spanning developmental biology, microtechnology, organ-on-chip systems, and biomaterials, to build a holistic understanding of how we can engineer human tissue models.

Today, I'm focused on the computational side of organoid biology: single-cell analysis, machine learning for biological data, and building the tools that will help us extract deeper meaning from these remarkable model systems.

2

Publications

6+

Research Labs

5.57

GPA / 6 (EPFL)

Code

Open source work and computational biology projects

View all repositories on GitHub

github.com/nickmahtani

Single-Cell Analysis Pipelines

Reproducible scRNA-seq workflows for organoid transcriptomic data, following approaches from leading computational biology groups.

PythonScanpyscRNA-seq

ML for Biological Data

Machine learning models applied to computational genomics problems, from coursework by Manolis Kellis (MIT) and Aaron Quinlan.

Pythonscikit-learnGenomics

Bioinformatics Toolkit

Scripts and notebooks for biological data analysis, visualization, and pipeline automation.

RBashJupyter

Research

2024 - 2025

Scientific Assistant

Lab of Chemical Nanotechnology (CHEMINA), EPFL

DNA aptamer-based biosensing for neurotransmitter detection

2022 - 2023

Master's Thesis (ZKS Fellow)

Mooney Lab, Harvard University

Macroporous alginate scaffolds for tendon tissue engineering

2022

Industry Intern

CSEM, Neuchâtel

Microfluidic perfusion systems for liver organoid culture

2021 - 2022

Research Assistant

Lütolf Lab, EPFL

Liver organoid-on-chip microfluidic cultures & vasculature

2021

Research Assistant

Aztekin Lab, EPFL

In vitro AER cell systems for limb regeneration

2019 - 2020

Research Assistant

Lab for Immuno Bioengineering, NYU Abu Dhabi

High-throughput bioprinting of immune cell-laden scaffolds

Publications

Videos

Cell Stories

Science Explainers

YouTube videos where I break down complex research topics in tissue engineering and cell biology into engaging, accessible explanations.

Watch on YouTube

Music

Vocal Performances

Singing has been a lifelong passion. From performing as a tenor in the AUS Choir to recording covers, music is how I recharge and express creativity beyond the lab.

Listen to covers

The Brain Hub Podcast

Co-founder & Host

A podcast I co-founded to give early-career researchers in medicine and biomedical engineering a platform to share their journeys, the motivation behind their work, and the impact they hope to achieve.

Listen to episodes

Theatre & Music

Performing arts have shaped how I communicate, collaborate, and think creatively.

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Little Shop of Horrors

Cast · AUS Performing Arts

2016

Flashbacks

Actor · AUS Performing Arts

2017

Alice in Wonderland

Bass (Orchestra) · AUS Performing Arts

2018

AUS Choir

Tenor · American University of Sharjah

2016 - 2019

Writing

Thoughts on science, career, and the spaces in between

PersonalComing soon

Why I Left My PhD

Reflections on recognizing when a path isn't right and having the courage to redirect toward what truly drives you.

ScienceComing soon

The Organoid Revolution

How miniature organ models are changing the way we study human biology and develop new therapies.

CareerComing soon

From Wet Lab to Dry Lab

My journey transitioning from bench-side tissue engineering to computational biology and bioinformatics.

Presentations

Integrating DNA Aptamers with Focal Molography for Neurotransmitter Sensing

Maxwell Biosystems Summit 2024Poster

Aptamer-Based Biosensing in Complex Biofluids

Symposium on Parkinson's Disease and Related Disorders 2024Poster

Pore Forming Alginate Gels with Tunable Porosity Affect Tendon Derived Cell Behavior

ORS 2024Poster

Bookshelf

What I'm reading and what shaped my thinking

Currently Reading

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Recently Finished

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Recommended

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